
LactoSpore®: A Dual-Action Probiotic for IBS and Mental Wellbeing
IBS doesn’t just affect the digestive system—it impacts mental health, emotional stability, and overall quality of life. For the millions suffering from bloating, abdominal pain, and unpredictable bowel habits, a holistic solution is long overdue.
LactoSpore®, a patented strain of Bacillus coagulans MTCC 5856, offers a science-backed, natural option that addresses both IBS symptoms and the anxiety or depression that often accompany them.
What Is LactoSpore®?
LactoSpore® is a spore-forming, shelf-stable probiotic designed to survive harsh stomach acid and reach the gut intact. Once in the intestine, it promotes microbial balance, reduces inflammation, and supports the gut-brain axis—a key pathway connecting digestive health with mood regulation.
Clinical Evidence: IBS Relief and Mood Improvement

In a randomized, double-blind, placebo-controlled study published in Nutrition Journal (2016), 36 patients with diagnosed IBS were given Bacillus coagulans MTCC 5856 (LactoSpore®) at 2 billion CFU per day for 90 days.
Results showed:
- Significant reduction in abdominal pain, bloating, and bowel irregularity
- Notable improvement in quality of life scores measured by IBS-QOL questionnaires
- Decrease in symptoms of depression, as assessed by standard psychiatric scales
These improvements were seen without any adverse effects, demonstrating LactoSpore®’s excellent safety and tolerability—even with long-term use.
Gut-Brain Connection: Why Mood Improves with Gut Healing
IBS is often linked to low-grade intestinal inflammation and dysbiosis, which can alter neurotransmitter balance and increase stress hormone levels. This condition—commonly called “IBS-related depression”—creates a feedback loop of worsening mental and gut symptoms.
LactoSpore®’s effectiveness lies in its ability to restore microbiota balance, reduce inflammatory markers, and regulate serotonin production—key mechanisms in both gut and mood health.
Why Choose LactoSpore®?
- ✅ Clinically validated for both IBS-D and IBS-C
- ✅ Targets both digestive and emotional symptoms
- ✅ Survives stomach acid and does not require refrigeration
- ✅ Suitable for long-term use, including alongside medications or dietary interventions
Conclusion
LactoSpore® is more than just a gut-friendly probiotic. It represents a new generation of targeted, science-backed solutions for patients with IBS who also struggle with anxiety, depression, or low quality of life.
If you’ve tried diet changes, medications, or generic probiotics without real relief, Bacillus coagulans MTCC 5856 may offer the breakthrough your body—and mind—have been waiting for.